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Is Long Covid a Death Sentence?
In General Discussion
siva.chander
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Jul 26, 2022
There's recent evidence that two peptides expressed by SARS-CoV-2 can self-assemble into Amyloid plaque tissue similar to the Prion protein that is implicated in the TSE (Transmissible Spongiform Encephalopathy) diseases like Scrapie, Kuru, BSE (Mad Cow disease), and so on. These are very long-term neural degenerative diseases, leading to death over time-frames of decades - the last documented Kuru death was recorded in 2009, though the causal agent was identified in the '60s. https://pubmed.ncbi.nlm.nih.gov/35697699/ Summary: Two peptides expressed by SARS-CoV-2 (but not SARS-CoV-1) self-assemble to amyloid tissue (aka Prions) and are very significantly neurotoxic. Explains Long Covid directly as a prion-induced degenerative neural condition. Also notes that SARS2 is different from SARS1, due to the lack of documented long-term neurological effects from SARS1. Quote: "It is also interesting that ORF10 and ORF8 are the only two coded proteins present in SARS-CoV-2 which do not have a homologue in SARS-CoV-1, perhaps suggesting a unique amyloid etiology for COVID-19. While long-term consequences from SARS-CoV-1 infection were severe, including tiredness, depression, and impaired respiration, few or zero unequivocally neurological post-viral symptoms were recorded from the (admittedly quite small) set of documented cases." So, yes, Long Covid seems to be a death sentence in the long term. But so is birth, if timescales equal to a century or so are considered.
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siva.chander

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I love canned Sardi!
Do I look sick?
Got it going on
Dead Poets Society
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